RNA Details
Disease Name
nephritis interstitia
Tissue
kidney
RNA Symbol
mir-181a-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
NA
Target
EGR1
Pathway
NA
PubMed ID
Title
High glucose down-regulates microRNA-181a-5p to increase pro-fibrotic gene expression by targeting early growth response factor 1 in HK-2 cells
Year
2017
Function
"Egr1 expression, which can be suppressed by miR-181a-5p directly, plays a crucial role in the progression of renal fibrosis in diabetic nephropathies."